Prior Adenoma and Colorectal Cancer Risk in Older Adults

Colonoscopy findings inform colorectal cancer (CRC) risk stratification, but their clinical relevance may shift with age. In older adults, the presence of a prior adenoma signals increased CRC risk, yet absolute risk remains low and must be weighed against competing mortality. This quiz, based on a retrospective cohort study published in JAMA, reviews the relationship between prior adenoma findings, future CRC risk, and why those risks may matter differently in older adults.