Featured

FDA Approval
spilled pill bottle
FDA Approval
FDA Expands Joenja Approval to Children Aged 4 to 11 Years With APDS
09/25/2026
Anthony Calabro, MA
Pediatric safety and pharmacokinetic findings supported expanding leniolisib to children aged 4 to 11 years who weigh at least 27 kg, establishing the first FDA-approved treatment for activated...
09/25/2026
Research Summary
sick child in bed
Research Summary
Decline in Influenza Antiviral Use in Hospitalized US Children Persists After COVID-19 Pandemic
09/24/2026
Kate Young
A multisite surveillance study published in Pediatrics assessed trends and determinants of influenza antiviral use in hospitalized children across the United States before and during the late COVID-19...
09/24/2026
Research Summary
human circulatory system
Research Summary
Bempedoic Acid Reduces First Major Adverse Limb Events in Statin-Intolerant Patients With PAD
09/24/2026
Anthony Calabro, MA
In a post hoc analysis of the randomized CLEAR Outcomes trial, bempedoic acid 180 mg reduced first major adverse limb events (MALE) by 36% and total MALE by 45% versus placebo among statin-intolerant...
09/24/2026

Clinical Insights

Editorial
Close up of black patient
Editorial
Recognizing National Sickle Cell Awareness Month
09/15/2026
Ashton L. Stahl
In recognition of National Sickle Cell Awareness Month, this editorial highlights the lifelong effects of sickle cell disease and the clinical vigilance needed to identify rare, life-threatening...
09/15/2026
Expert Q&A
John W Harrington, MD
Expert Q&A
Newborn Vitamin K Shot Refusals Increase, Raising Bleeding Concerns
09/14/2026
John W. Harrington, MD
A Reuters analysis found that the proportion of US newborns who did not receive a vitamin K injection within 1 day of birth increased by more than 57% from January through June 2026.
09/14/2026
Video
Robert Hegele, MD
Video
Managing Severe Hypertriglyceridemia: Identifying Chylomicronemia Syndrome and Reducing Pancreatitis Risk
09/11/2026
Robert Hegele, MD
In this video interview, Robert Hegele, MD, discusses the diagnosis and management of sHTG-related chylomicronemia syndrome, including strategies to reduce the risk of pancreatitis, dietary interventions,...
09/11/2026
Video
Drs Antevy and Piehl
Video
Managing Pediatric Hemorrhagic Shock With a Circulation-First Approach
09/07/2026
Peter M. Antevy, MD; Mark Piehl, MD, MPH
In this video Q&A, Peter Antevy, MD, and Mark Piehl, MD, preview their EMS World Expo session on circulation-first resuscitation in pediatric trauma.
09/07/2026
Expert Q&A
Brady L Stein, MD
Expert Q&A
How the ASH Clinical Practice Guidelines Aim to Improve Myelofibrosis Management
08/26/2026
Brady L. Stein, MD
At the 2025 American Society of Hematology (ASH) Annual Meeting, Brady Stein, MD, chaired a session introducing the forthcoming ASH Clinical Practice Guidelines on Myelofibrosis—the first ASH-supported...
08/26/2026

From the Journal

What's Your Diagnosis?
Widespread urticarial plaques with tense bullae over the patients' legs
What's Your Diagnosis?
Pruritic Urticarial Plaques and Tense Bullae During a Second Trimester Pregnancy
09/20/2026
Elen Deng, BS; Jill Stachowski, BS; Marc Schlessel, MD; Thomas N. Helm, MD
A 34-year-old woman at 24 weeks gestation presented to the dermatology clinic with a 1-month history of worsening, painful, and pruritic skin eruption.
09/20/2026
What's the Take Home?
man talking with physician
What's the Take Home?
A 55-Year-Old Man with Neurologic, Hematologic Abnormalities
09/19/2026
Ronald N. Rubin, MD
A 55-year-old man presents with a subacute history of an unsteady, stumbling gait resulting in several falls during the last 2 weeks.
09/19/2026
What's The Take Home?
woman with shortness of breath
What's The Take Home?
A 44-Year-Old Woman With Worsening Fatigue and Shortness of Breath With Exertion
09/12/2026
Ronald N. Rubin, MD
A 44-year-old woman presents for evaluation with new fatigue and worsening shortness of breath with exertion. The patient noted that she has valvular heart disease related to an episode of rheumatic fever...
09/12/2026
What's the Take Home?
woman with bags traveling at the airport
What's the Take Home?
A Healthy 18-Year-Old Presents With Questions About Travel Vaccinations
09/06/2026
Ronald N. Rubin, MD
An 18-year-old high school senior and her parents present to their long-time family physician's office with questions about travel vaccinations.
09/06/2026
Photoclinic
Figure 1. An 8-year-old boy presents with symmetric bald patches since birth in the temporal area.
Photoclinic
Temporal Triangular Alopecia
09/05/2026
Shae Margulies, MD; Stephanie Ryan, MD
An 8-year-old boy presents with symmetric bald patches in the temporal area which have been present his entire life.
09/05/2026