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Depression Care360
an adult and child stand below a tree
Depression Care360
Early-Life Adversity Strongly Associated With Antidepressant Resistance in Major Depression
03/18/2026
A recent cohort study found that adverse childhood experiences (ACEs) are strongly associated with treatment-resistant depression (TRD), even after accounting for familial and genetic confounding.
03/18/2026
Depression Care360
pills spilling out of a tipped over pill bottle
Depression Care360
Meta-Analysis Reinforces Link Between SSRIs and Sexual Dysfunction in Adults With Depression
03/04/2026
Selective serotonin reuptake inhibitors (SSRIs) are associated with a significantly increased risk of sexual dysfunction in adults treated for depression, according to a systematic review and...
03/04/2026
Depression Care360
a sticky note that reads "take the quiz" stuck to a computer keyboard
Depression Care360
Antidepressant Deprescribing in Remitted Depression
02/10/2026
Test your knowledge of recent research with this quick quiz!
02/10/2026

Interactive Features

Depression Care360
a sticky note that reads "take the quiz" stuck to a computer keyboard
Depression Care360
Antidepressant Deprescribing in Remitted Depression
02/10/2026
Test your knowledge of recent research with this quick quiz!
02/10/2026
Depression Care360
Brittany Albright, MD, MPH
Depression Care360
Assessing and Managing Anhedonia
10/07/2025
Refresh your knowledge of these clinical pearls from Brittany Albright, MD, MPH.
10/07/2025
Depression Care360
sticky note that reads "take the quiz"
Depression Care360
Nonresponse or Partial Response in Antidepressant Treatment
08/01/2025
Test your knowledge of the APA guideline recommendations for depression treatment!
08/01/2025
Faculty Insights Quiz
Craig Chepke, MD, DFAPA
Faculty Insights Quiz
Kappa Receptor Antagonists' Role in MDD Treatment
04/17/2025
Craig Chepke, MD, DFAPA
As seen in a recent interview with Psych Congress Scientific Director Craig Chepke, MD, DFAPA, kappa receptor antagonists have shown potential as a treatment to target which MDD symptom?
04/17/2025
Depression Care360
Expert Insights Quiz
Depression Care360
Why do conventional antidepressants often fail to treat anhedonia?
03/11/2025
Why do conventional antidepressants, such as SSRIs, often fail to effectively treat anhedonia? Take the quiz to test your knowledge.
03/11/2025

Clinical Insights

Depression Care360
Veronica Ridpath, DO
Depression Care360
Thinking Beyond Monoamines in Depression Treatment
01/14/2026
Veronica Ridpath, DO, Psych Congress Elevate faculty member, discusses how evolving understanding of the biological pathways involved in depression is changing the landscape of treatment approaches.
01/14/2026
Depression Care360
Craig Chepke, MD, DFAPA, and Kristian Dambrino, DNP, PMHNP-BC
Depression Care360
Leveraging Glutamatergic Antidepressants for the Treatment of MDD
09/09/2025
An insightful discussion between Craig Chepke, MD, DFAPA, and Kristian Dambrino, DNP, PMHNP-BC.
09/09/2025
Depression Care360
Julie Carbray and Kristian Dambrino
Depression Care360
How New Technologies are Shaping the Future of Depression Treatment
06/02/2025
06/02/2025
Depression Care360
Julie Carbray and Kristian Dambrino
Depression Care360
Clinical Implications and Potential Benefits of Newer Treatments for Depression
05/20/2025
05/20/2025
Depression Care360
Headshots of Dr Julie Carbray and Kristian Dambrino
Depression Care360
The Role of NMDA and AMPA Receptors in Rapid-Acting Antidepressant Treatments
05/07/2025
In part 1 of this series, Julie Carbray, PhD, PMHNP-BC, PMHCNS-BC, APRN, and Kristian Dambrino, DNP, PMHNP-BC, discuss the role NMDA and AMPA receptors play in depression treatment.
05/07/2025

Research Summaries

Depression Care360
an adult and child stand below a tree
Depression Care360
Early-Life Adversity Strongly Associated With Antidepressant Resistance in Major Depression
03/18/2026
A recent cohort study found that adverse childhood experiences (ACEs) are strongly associated with treatment-resistant depression (TRD), even after accounting for familial and genetic confounding.
03/18/2026
Depression Care360
pills spilling out of a tipped over pill bottle
Depression Care360
Meta-Analysis Reinforces Link Between SSRIs and Sexual Dysfunction in Adults With Depression
03/04/2026
Selective serotonin reuptake inhibitors (SSRIs) are associated with a significantly increased risk of sexual dysfunction in adults treated for depression, according to a systematic review and...
03/04/2026
Depression Care360
a woman sitting on the edge of a bed
Depression Care360
Racemic Ketamine Matches Esketamine in Depressive Symptom Reduction for TRD
02/03/2026
Racemic ketamine was noninferior to intranasal esketamine for reducing depressive symptoms in adults with treatment-resistant depression (TRD) over 4 weeks.
02/03/2026
Depression Care360
woman looks out window
Depression Care360
Meta-Analysis Links Anti-Inflammatory Therapy to Reduced Anhedonia
01/02/2026
Anti-inflammatory treatments significantly reduced anhedonia and depressive symptom severity in patients with depression and elevated inflammation.
01/02/2026
Depression Care360
holding hands
Depression Care360
Slow Supported Antidepressant Taper Matches Continuation for Depression Relapse Prevention
12/17/2025
A new systematic review and network meta-analysis has found that slow antidepressant tapering combined with psychological support is as effective as continuation therapy in preventing relapse in adults with...
12/17/2025