Research Summaries

Pediatric safety and pharmacokinetic findings supported expanding leniolisib to children aged 4 to 11 years who weigh at least 27 kg, establishing the first FDA-approved treatment for activated...

A multisite surveillance study published in Pediatrics assessed trends and determinants of influenza antiviral use in hospitalized children across the United States before and during the late COVID-19...

In a post hoc analysis of the randomized CLEAR Outcomes trial, bempedoic acid 180 mg reduced first major adverse limb events (MALE) by 36% and total MALE by 45% versus placebo among statin-intolerant...

A randomized trial compared three antithrombotic agents with metoprolol for migraine prevention in adults with patent foramen ovale.

Results from the SOHO-01 trial supported expanded use of sevabertinib in adults with HER2-mutated, locally advanced or metastatic nonsquamous non–small cell lung cancer, including patients who had not...

CDC retained prior influenza vaccine recommendations for 2026–2027 and detailed vaccine selection, timing, dosing, and precautions.

In an emulated trial of 56,652 matched pairs with COPD, vaccination was associated with a 39% lower hazard of hospitalized influenza.

In an open-label extension, cliramitug reduced cardiac amyloid markers over a median 29.3 months in 23 men with ATTR-CM.

In a multisite nonrandomized trial, AI-guided screening identified ATTR-CM in 24 of 50 patients who completed diagnostic testing.

Phase 3 explorer8 data showed daily concizumab maintained low bleeding rates through 56 weeks in hemophilia A or B without inhibitors.