Researchers compared high-dose versus standard-dose influenza vaccines in adults aged 65 to 79 years to determine whether enhanced immunogenicity translates into reduced severe clinical outcomes, including...
A phase 3 trial evaluates whether first-line disitamab vedotin combined with toripalimab could improve outcomes compared with platinum-based chemotherapy in patients with previously untreated...
The FDA has cleared a once-daily oral semaglutide treatment for adults with obesity or overweight and weight-related conditions, based on phase 3 OASIS 4 trial results demonstrating significant mean weight...
A new ACC/AHA clinical practice guideline on managing adults with congenital heart disease updates its 2018 recommendations by integrating evidence from 2017 to 2024 and emphasizing specialized...
Initiation of urate-lowering therapy (ULT) is frequently complicated by acute gout flares, and the need for safe and effective prophylaxis remains a challenge in clinical practice. A new phase 2 trial from...
A pooled analysis of 4 MagnetisMM trials evaluated dosing strategies for elranatamab, a BCMA-CD3 bispecific antibody, to identify the optimal regimen that mitigates cytokine release syndrome in patients...
A pooled analysis of two phase 3 ENHANCE trials evaluated whether the inhaled dual phosphodiesterase 3 and 4 inhibitor antifeminine reduces chronic obstructive pulmonary disease exacerbation frequency and...
In a retrospective review, researchers assessed the influence of preoperative peripheral nerve blocks (PNBs) on postoperative opioid use following total shoulder and knee surgeries. Their findings,...
