ADPKD Status Affects Mortality Rate in Patients on Dialysis

Patients with autosomal dominant polycystic kidney disease (ADPKD) who are on peritoneal dialysis have a lower mortality risk than patients without ADPKD who are on dialysis, according to a new study.

The results of the study were presented at the National Kidney Foundation’s 2018 Spring Clinical Meetings in April.

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To conduct their study, the researchers reviewed 12 observational studies that evaluated the risks of death, technique failure, and peritonitis in patients with ADPKD who were on peritoneal dialysis (n = 931).

Participants were analyzed against a control group of patients without ADPKD who were on peritoneal dialysis (n = 13,742).

Results of the researchers’ analysis showed that patients with ADPKD had a significantly lower mortality risk compared with patients without ADPKD. Risks for technique failure of peritoneal dialysis and peritonitis were not associated with ADPKD.

—Amanda Balbi

Reference:

Boonpheng B, Thongprayoon C, Wijarnpreecha K, et al. ESRD from Outcomes of patients with autosomal dominant polycystic kidney disease on peritoneal dialysis: a meta-analysis. Paper presented at: National Kidney Foundation 2018 Spring Clinical Meetings; April 10-14, 2018; Austin, TX. https://www.nkf2018scm.site/Abstracts/NKFSCM18/Gallery#!/b5d84d0e-6602-4763-8955-acbb1622fc70/abstract/7fe6d8b6-6924-42f9-bb04-006ac932015b/viewer. Accessed April 24, 2018.

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