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Endometrial Cancer Risk Factors
Endometrial cancer is influenced by a complex interplay of genetic, hormonal, and metabolic risk factors. Understanding these risk factors is crucial for both prevention and early detection, particularly as the incidence of endometrial cancer increases in premenopausal women. Several well-established contributors include hormonal imbalances such as unopposed estrogen exposure, metabolic syndromes like obesity and insulin resistance, and certain hereditary conditions. Risk stratification helps guide clinicians in counseling patients and assessing candidacy for fertility-sparing treatments.