Can You Distinguish Esophageal Squamous Cell Carcinoma from Esophageal Adenocarcinoma?

Esophageal squamous cell carcinoma (ESCC) remains a challenging malignancy with distinct epidemiologic and clinical features compared with its counterpart, esophageal adenocarcinoma. As Karyn A. Goodman, MD, MS, Professor and Vice Chair for Research and Quality in the Department of Radiation Oncology at the Icahn School of Medicine at Mount Sinai notes in her interview with Consultant360, understanding the differences in pathogenesis, risk factors, and anatomical origin is key to improving diagnostic precision and guiding early management decisions.

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