Kevin J. Downes, MD, on Procalcitonin as a Marker for Sepsis

In this podcast, Kevin Downes, MD, discusses procalcitonin as a marker for sepsis, how a procalcitonin test fares among other diagnostic tests, and how this testing can guide antibiotic stewardship.

Kevin J. Downes, MD, is an assistant professor of pediatrics at the Perelman School of Medicine at the University of Pennsylvania and an attending physician in the Division of Infectious Diseases at the Children's Hospital of Philadelphia (CHOP). He is also faculty of the Center for Pediatric Clinical Effectiveness and the Center for Clinical Pharmacology at CHOP.

Additional Resources:

  • Downes KJ. Procalcitonin as a marker for sepsis: a useful test or the best we have? Talk presented at: IDWeek 2019; October 2-6, 2019; Washington, DC. https://cdmcd.co/WxJYk.
  • Downes KJ, Weiss SL, Gerber JS, et al; Centers for Disease Control and Prevention Epicenters Program. A pragmatic biomarker-driven algorithm to guide antibiotic use in the pediatric intensive care unit: the Optimizing Antibiotic Strategies in Sepsis (OASIS) study. J Pediatric Infect Dis Soc. 2017;6(2):134-141. https://doi.org/10.1093/jpids/piw023.
  • Downes KJ, Fitzgerald JC, Schriver E, et al; Centers for Disease Control and Prevention Epicenters Program. Implementation of a pragmatic biomarker-driven algorithm to guide antibiotic use in the pediatric intensive care unit: the Optimizing Antibiotic Strategies in Sepsis (OASIS) II study [published online November 22, 2018]. J Pediatric Infect Dis Soc. https://doi.org/10.1093/jpids/piy113

 

Disclosures: 
Merck: Grant/Research Support, Research Grant
Pfizer: Grant/Research Support

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