Smoking Impacts Kidney Function in Arterial Hypertension
In patients with arterial hypertension, smoking is associated with significant increase in blood pressure and significantly reduced kidney function, according to a recent study.
To examine the relationship between smoking, nutritional status, and renal function in patients with arterial hypertension (AH), the researchers conducted a study of 53 patients with stage II AH (mean age 55 years) who were divided into groups based on smoking status (19 smokers vs 35 non-smokers).
The participants all underwent measurement of nutritional status using anthropometry and bioimpedancemetry using an Omrom analyzer, as well as measurement of urine creatinine and albumin.
In group I, systolic blood pressure was 155 (133; 164) mm Hg, diastolic blood pressure was 99 (87; 106) mm Hg, body mass index was 27.9 (24.0; 30.0) kg/m2, the percentage of total fat was 22.7 (17.8; 31.7), urine creatinine levels were 12,673 (9944; 15,460) µmol/L, and urine albumin level was 7.9 (3.9; 19.0) mg/mmol.
In group II, systolic blood pressure was 151 (128; 156) mm Hg, diastolic blood pressure was 94 (85; 103) mm Hg, body mass index was 28.3 (24.5; 31.1) kg/m2, the percentage of total fat was 39.4 (33.3; 44.5), urine creatinine levels were 4832 (3152; 11948) µmol/L, and urine albumin levels were 2.0 (0.6; 4.4) mg/mmol.
“A significant increase in blood pressure was found in smokers. Also, smokers with arterial hypertension showed a significant decrease in the content of adipose tissue. The function of the kidneys in smokers was significantly reduced, while at the same time it was revealed that with a decrease in the content of adipose tissue in patients with hypertension, the renal function was significantly worsened.”
Boiko O, Rodionova V. Relationship between smoking, nutritional status, and renal function in patients with arterial hypertension. CHEST. 2020. 158(4):Sup A137. https://doi.org/10.1016/j.chest.2020.08.155