Indication for Revision TKA Can Predict Outcomes and Patient Satisfaction
Key Highlights
- Postoperative KOOS-JR scores were highest after revision for polyethylene wear and lower after revision for arthrofibrosis or malalignment.
- Clinically important improvement occurred in 43.1% of arthrofibrosis cases versus 63.7% of aseptic loosening cases.
- Reoperation occurred in 25.8% of arthrofibrosis cases, compared with approximately 2.5%–9.1% for most other indications.
In a retrospective cohort study, patient-reported outcomes, satisfaction, and reoperation rates after revision total knee arthroplasty (rTKA) varied substantially by reason for revision. Arthrofibrosis and malalignment were associated with poorer postoperative scores and lower satisfaction, while arthrofibrosis carried the highest reoperation burden. The study was presented at the 2026 American Association of Hip and Knee Surgeons (AAHKS) Annual Meeting.
The investigators sought to clarify how outcomes differ across revision indications, which vary in etiology and complexity. They noted that revision TKA is increasing and imposes substantial patient and financial burdens, while differences in patient-reported results across indications remain incompletely characterized.
The single-center study evaluated rTKA cases performed from 2012 through 2023 across a multisite academic orthopedic practice. Investigators extracted revision indications from an institutional database and classified them into categories including periprosthetic joint infection (PJI), instability, arthrofibrosis, aseptic loosening, polyethylene wear, malalignment, wound complications, fracture, effusion, patellar resurfacing, extensor mechanism disruption, and other causes.
Outcomes included preoperative and latest available postoperative KOOS-JR scores, Knee Society Score satisfaction and expectation scores, and achievement of the KOOS-JR minimal clinically important difference (MCID). The analysis also evaluated reoperation rates by indication.
Study Findings
The cohort included 2,092 revision TKAs, most commonly performed for aseptic loosening (795), instability (509), and PJI (390). Median postoperative KOOS-JR was highest for polyethylene wear, at 76.6, compared with 52.5 for arthrofibrosis and 58.2 for malalignment. Postoperative satisfaction followed a similar pattern: scores were lowest for malalignment and arthrofibrosis (14 and 15.5, respectively) and highest for polyethylene wear and aseptic loosening (22 and 20).
MCID attainment also differed by indication. Among patients undergoing revision for arthrofibrosis, 43.1% achieved the KOOS-JR MCID, compared with 63.7% undergoing revision for aseptic loosening. Arthrofibrosis had the highest reported reoperation rate, at 25.8%; rates for most other indications were approximately 2.5%–9.1%. These findings reflect the indication-specific outcomes reported in the supplied cohort.
Clinical Implications
The authors suggest these differences support counseling patients based on their revision indication and developing targeted strategies to improve subjective outcomes in high-risk revision groups. They highlighted arthrofibrosis and malalignment because patients reported poorer outcomes and satisfaction, with additional concern about reoperation after revision for arthrofibrosis.
Expert Commentary
“These findings support indication-specific counseling and targeted strategies to improve subjective outcomes in high-risk revision groups,” the researchers concluded.
Reference
DeSimone CA, Tecce E, Leipman JH, Sellig MT, Sherman MB, Fillingham YA. The indication for revision TKA predicts postoperative patient reported outcomes and satisfaction. Paper #21. Abstract presented at the American Association of Hip and Knee Surgeons Annual Meeting, November 5–8, 2026, Dallas, TX.
