Oncology

A randomized clinical trial tested whether a digital health program delivered directly to patients could increase lung cancer screening rates among eligible adults. Conducted at two academic health systems,...

A phase 2 nonrandomized clinical trial explored whether breast surgery could be safely eliminated for women with ERBB2-positive or triple-negative invasive breast cancer who achieved a pathologic complete...

A randomized controlled trial found that both transdiscal and paraspinal splanchnic nerve block approaches effectively reduced pain in advanced pancreatic cancer, with the transdiscal technique offering...

A randomized trial in breast cancer survivors found that just one session of resistance or high-intensity interval training significantly elevated circulating anti-cancer myokines and reduced the growth of...

The phase 3 SERENA-6 trial evaluated whether replacing an aromatase inhibitor with camizestrant while continuing a CDK4/6 inhibitor in patients with ER-positive, HER2-negative advanced breast cancer and...

Emerging research explores how a wearable device may identify infection before symptoms appear, which treatments reduce hospitalizations, and who remains most at risk.

A new randomized trial in newly formed heterosexual couples investigated whether recent human papillomavirus vaccination protects individuals or their partners against transmission.

In a phase 3 trial, trastuzumab deruxtecan significantly extended overall survival compared with ramucirumab plus paclitaxel in previously treated patients, with manageable toxicity and mostly low-grade...

A large randomized trial found that mailing unsolicited fecal immunochemical test kits increased colorectal cancer screening rates among adults aged 45 to 49 compared with strategies requiring patients to...

The FDA approved Zongertinib for adults with unresectable or metastatic non-squamous NSCLC with HER2 (ERBB2) TKD activating mutations following prior systemic therapy.