An open-label, randomized trial found that daratumumab and hyaluronidase-fihj administered subcutaneously improved the risk of disease progression or death in patients with multiple myeloma. As a result,...
A large, real-world comparative analysis evaluated 1-year clinical and safety outcomes among patients with chronic lymphocytic leukemia receiving venetoclax-based versus Bruton's tyrosine kinase...
A phase 2 trial from the University of Miami evaluated whether combining iberdomide with carfilzomib, daratumumab, and dexamethasone could induce deep responses—including MRD-negativity—in patients with...
A phase 1b–2 trial published in The New England Journal of Medicine evaluated the combination of two bispecific antibodies, talquetamab and teclistamab, for patients with relapsed or refractory multiple...
For oncologists considering immunotherapy sequencing, a Nature report from MD Anderson Cancer Center in Houston, TX, suggests that receipt of a SARS-CoV-2 mRNA vaccine near the start of immune checkpoint...
A randomized clinical trial tested whether a digital health program delivered directly to patients could increase lung cancer screening rates among eligible adults. Conducted at two academic health systems,...
A phase 2 nonrandomized clinical trial explored whether breast surgery could be safely eliminated for women with ERBB2-positive or triple-negative invasive breast cancer who achieved a pathologic complete...
A randomized controlled trial found that both transdiscal and paraspinal splanchnic nerve block approaches effectively reduced pain in advanced pancreatic cancer, with the transdiscal technique offering...
A randomized trial in breast cancer survivors found that just one session of resistance or high-intensity interval training significantly elevated circulating anti-cancer myokines and reduced the growth of...
The phase 3 SERENA-6 trial evaluated whether replacing an aromatase inhibitor with camizestrant while continuing a CDK4/6 inhibitor in patients with ER-positive, HER2-negative advanced breast cancer and...