In adults with chronic low back pain managed with long-term opioids, a large, randomized, clinical trial evaluated whether mindfulness-based therapy offers superior outcomes compared with cognitive...
A randomized US trial evaluated whether a shortened course of romosozumab followed by denosumab could achieve bone mineral density improvements comparable to the standard 12-month romosozumab regimen in...
A pair of randomized clinical trials published in JAMA investigated whether adding acetaminophen or an opioid analgesic to ibuprofen improves pain relief for children with acute musculoskeletal injuries,...
In a retrospective review, researchers assessed the influence of preoperative peripheral nerve blocks (PNBs) on postoperative opioid use following total shoulder and knee surgeries. Their findings,...
An open-label, randomized trial found that daratumumab and hyaluronidase-fihj administered subcutaneously improved the risk of disease progression or death in patients with multiple myeloma. As a result,...
A multicenter randomized trial evaluated whether adding supervised physical therapy sessions or adherence-promoting text messages to a home-exercise program offers greater pain relief for adults with...
A large cohort study from a quaternary health center found that using β-lactam antibiotics for surgical prophylaxis significantly lowered the risk of surgical site infections compared with non–β-lactam...
Debridement, Antibiotics, and Implant Retention (DAIR) achieved comparable long-term outcomes whether performed within 4 weeks or between 5 and 12 weeks after arthroplasty for acute prosthetic joint...
A national database analysis found that outpatient total knee arthroplasty (oTKA) is associated with significantly fewer 30-day complications compared to inpatient procedures, a trend that held steady...
Intravenous (IV) dexamethasone may significantly reduce pain scores following total knee arthroplasty (TKA), but questions remain about the ideal dose and timing. To fill this gap, researchers conducted a...
