In a retrospective, propensity score-matched national cohort of adults with type 2 diabetes mellitus undergoing primary total knee arthroplasty, semaglutide and tirzepatide were associated with similar...
A 52-week trial evaluated apitegromab-mstn as an adjunct to SMN2-targeted treatment in patients with spinal muscular atrophy who could not move or walk independently, demonstrating improved motor function...
In the double-blind EPCAT III RCT, aspirin alone was noninferior to 5 days of rivaroxaban followed by aspirin for preventing symptomatic VTE after total hip or knee arthroplasty, with no clinically relevant...
A randomized clinical trial evaluating 2 types of 1-page educational resources for low back pain found that fact sheets listing treatment options modestly improved patients’ preparedness for shared...
Using real-world patient scenarios and current guideline recommendations, this session from Practical Updates in Primary Care outlines a structured primary care approach to diagnosing low back pain,...
In adults with chronic low back pain managed with long-term opioids, a large, randomized, clinical trial evaluated whether mindfulness-based therapy offers superior outcomes compared with cognitive...
A randomized US trial evaluated whether a shortened course of romosozumab followed by denosumab could achieve bone mineral density improvements comparable to the standard 12-month romosozumab regimen in...
A pair of randomized clinical trials published in JAMA investigated whether adding acetaminophen or an opioid analgesic to ibuprofen improves pain relief for children with acute musculoskeletal injuries,...
In a retrospective review, researchers assessed the influence of preoperative peripheral nerve blocks (PNBs) on postoperative opioid use following total shoulder and knee surgeries. Their findings,...
