Orthopedics

Researchers created a mouse model of osteoglophonic dysplasia to better understand why the condition causes excess FGF23, low phosphate levels, and abnormal bone development.

Researchers created a mouse model of hypochondroplasia that showed memory problems and a much higher susceptibility to seizures, similar to neurological issues seen in some people with the condition.

Researchers tested whether the dose of infigratinib used to treat children with achondroplasia also interferes with FGFR1, a related receptor that could cause adverse effects.

A survey review examined gastrointestinal symptoms in adults with skeletal dysplasias, including osteogenesis imperfecta.

Researchers examined bone, cartilage, muscle, and mitochondrial pathways in a mouse model of hypochondroplasia.

A retrospective review examined hearing loss and middle ear dysfunction in 45 children with osteogenesis imperfecta.

Researchers assessed vertebral fracture prevalence, new fractures, and fracture burden across patients of varying ages with untreated osteogenesis imperfecta type I.

Research presented at ASBMR 2026 identified changes in purine and lipid metabolism that may point to biomarkers for craniometaphyseal dysplasia.

The meeting will highlight new research and treatments for rare bone diseases, skeletal dysplasias, and other bone and musculoskeletal conditions.

In a retrospective, propensity score-matched national cohort of adults with type 2 diabetes mellitus undergoing primary total knee arthroplasty, semaglutide and tirzepatide were associated with similar...