In adults with chronic low back pain managed with long-term opioids, a large, randomized, clinical trial evaluated whether mindfulness-based therapy offers superior outcomes compared with cognitive...
A randomized US trial evaluated whether a shortened course of romosozumab followed by denosumab could achieve bone mineral density improvements comparable to the standard 12-month romosozumab regimen in...
A pair of randomized clinical trials published in JAMA investigated whether adding acetaminophen or an opioid analgesic to ibuprofen improves pain relief for children with acute musculoskeletal injuries,...
In a retrospective review, researchers assessed the influence of preoperative peripheral nerve blocks (PNBs) on postoperative opioid use following total shoulder and knee surgeries. Their findings,...
An open-label, randomized trial found that daratumumab and hyaluronidase-fihj administered subcutaneously improved the risk of disease progression or death in patients with multiple myeloma. As a result,...
A multicenter randomized trial evaluated whether adding supervised physical therapy sessions or adherence-promoting text messages to a home-exercise program offers greater pain relief for adults with...
A large cohort study from a quaternary health center found that using β-lactam antibiotics for surgical prophylaxis significantly lowered the risk of surgical site infections compared with non–β-lactam...
Debridement, Antibiotics, and Implant Retention (DAIR) achieved comparable long-term outcomes whether performed within 4 weeks or between 5 and 12 weeks after arthroplasty for acute prosthetic joint...
A national database analysis found that outpatient total knee arthroplasty (oTKA) is associated with significantly fewer 30-day complications compared to inpatient procedures, a trend that held steady...
