The phase 3 SERENA-6 trial evaluated whether replacing an aromatase inhibitor with camizestrant while continuing a CDK4/6 inhibitor in patients with ER-positive, HER2-negative advanced breast cancer and...
A multilevel intervention improved human papillomavirus vaccine initiation and completion among most children aged 11 to 12 years, though the effect was limited for those living in under-resourced settings,...
In a large multicenter randomized trial, intrapartum oral sildenafil citrate did not reduce adverse perinatal outcomes related to fetal hypoxia compared with placebo.
Nestoras Mathioudakis, MD, MHS, shares findings from a randomized controlled trial comparing a fully automated, app-based diabetes prevention program with a standard CDC-recognized intervention,...
A study presented at the 85th Scientific Sessions of the American Diabetes Association explored how physical and cognitive limitations affect glucometer use in adults aged 65 years and older with type 2...
In women with dense breast tissue and a negative screening mammogram, abbreviated MRI and contrast-enhanced mammography tripled the detection rate of invasive breast cancer compared with automated breast...
The 2025 American Society of Clinical Oncology guideline update redefines the role of sentinel lymph node biopsy (SLNB) in early-stage breast cancer. Building on evidence from major trials, the update...
Patients with higher education levels and scheduled colorectal surgeries were significantly more likely to exhibit adequate health literacy, better understanding of their care, and greater trust in their...
Researchers introduced an updated educational pamphlet for outpatient management of peripheral nerve block catheters, resulting in a reduction in patient calls and improved adherence to multimodal analgesia...
Despite advancements in guideline-directed therapy, heart failure readmissions remain high. At the American College of Physicians Internal Medicine Meeting 2025, Shudhanshu Alishetti, MD, outlined how...