In adults with chronic low back pain managed with long-term opioids, a large, randomized, clinical trial evaluated whether mindfulness-based therapy offers superior outcomes compared with cognitive...
In a large, multicenter US randomized clinical trial, investigators tested whether initiating a 7-day extended-release injectable buprenorphine formulation in the emergency department (ED) could improve...
A pair of randomized clinical trials published in JAMA investigated whether adding acetaminophen or an opioid analgesic to ibuprofen improves pain relief for children with acute musculoskeletal injuries,...
In a retrospective review, researchers assessed the influence of preoperative peripheral nerve blocks (PNBs) on postoperative opioid use following total shoulder and knee surgeries. Their findings,...
A new retrospective claims analysis evaluated adherence to extended-release buprenorphine and its impact on healthcare resource utilization and cost among commercially insured patients with opioid use...
A new study comparing robotic and laparoscopic cholecystectomies found no significant difference in perioperative opioid use or operative time between the two approaches. These findings were presented at...
In a national analysis spanning more than two decades, researchers found that fentanyl-stimulant overdose deaths among adults aged 65 years and older have surged 9000% since 2015, revealing that older...
Gabapentin did not reduce pain or opioid use after orthognathic surgery and was associated with higher consumption of analgesics despite some benefit in reducing nausea, according to the authors of a...
The FDA has announced mandatory labeling changes for all opioid pain medications to more clearly communicate the risks associated with long-term use, including addiction, overdose, and other serious harms....
In a single-center retrospective cohort study, patients who received the RECK (ropivacaine-epinephrine-clonidine-ketorolac) cocktail during posterior spinal fusion experienced significantly lower...
