A pair of randomized clinical trials published in JAMA investigated whether adding acetaminophen or an opioid analgesic to ibuprofen improves pain relief for children with acute musculoskeletal injuries,...
In a retrospective review, researchers assessed the influence of preoperative peripheral nerve blocks (PNBs) on postoperative opioid use following total shoulder and knee surgeries. Their findings,...
A new retrospective claims analysis evaluated adherence to extended-release buprenorphine and its impact on healthcare resource utilization and cost among commercially insured patients with opioid use...
A new multicenter analysis presented at the 67th American Society of Hematology (ASH) Annual Meeting evaluates how often emergency departments meet national guidelines for timely opioid administration in...
A new study comparing robotic and laparoscopic cholecystectomies found no significant difference in perioperative opioid use or operative time between the two approaches. These findings were presented at...
Gabapentin did not reduce pain or opioid use after orthognathic surgery and was associated with higher consumption of analgesics despite some benefit in reducing nausea, according to the authors of a...
The FDA has announced mandatory labeling changes for all opioid pain medications to more clearly communicate the risks associated with long-term use, including addiction, overdose, and other serious harms....
A retrospective cohort study found that patients undergoing outpatient GI procedures who received opioids intra- or post-operatively reported lower pain scores and fewer instances of postoperative nausea...
A system-wide reduction in default opioid prescriptions modestly decreased opioid dispensing but increased refill rates, highlighting ongoing disparities in postoperative pain management, according to the...
A randomized phase 3 trial evaluated cebranopadol, a dual-NMR agonist, for postoperative pain after abdominoplasty and found reduced pain and opioid use. This study was presented on May 1, 2025, at the ASRA...
