The FDA has approved Avlayah (tividenofusp alfa-eknm) for certain pediatric patients with Hunter syndrome, marking the first approval targeting the disease's neurologic complications and offering clinicians...
The results from a recent randomized controlled trial showed that ultrasound-guided sphenopalatine ganglion (SPG) and greater occipital nerve blocks are equally effective in reducing headache frequency,...
A phase 3 randomized trial evaluated the efficacy and safety of fremanezumab for preventive treatment of episodic migraine in children and adolescents, addressing a significant evidence gap in pediatric...
A phase 4 TANDEM trial in the United States evaluated whether ubrogepant for acute migraine treatment can be safely added to atogepant and used daily for preventive therapy in adults with episodic migraine,...
A large cross-sectional Italian study evaluated the prevalence of cognitive frailty and identified HIV-specific and clinical risk factors among adults 50 years or older living with HIV, highlighting the...
A large U.S. multicenter analysis compared early surgical evacuation versus initial conservative management for acute subdural hematoma in patients with traumatic brain injury. Results, published in JAMA...
A meta-analysis published in GeroScience evaluated data from 23 studies to determine the impact of adherence to the Mediterranean diet on the risk of cognitive impairment, dementia, and Alzheimer disease....
In a recent study, exposure to fine particulate matter (PM2.5) was associated with both more advanced Alzheimer disease neuropathologic change and greater dementia severity, with much of this link mediated...
In a phase 3 randomized controlled trial, escitalopram was not associated with significant improvement in agitation symptoms in patients with Alzheimer dementia and was linked to QT interval prolongation,...
The FDA initiated approval of leucovorin calcium tablets to treat cerebral folate deficiency (CFD) following a systematic analysis demonstrating promise in this patient population.
