Research Summaries

Research Summary
Research Summary
11/10/2025
Kate Young
A meta-analysis published in GeroScience evaluated data from 23 studies to determine the impact of adherence to the Mediterranean diet on the risk of cognitive impairment, dementia, and Alzheimer disease....
11/10/2025
Research Summary
Research Summary
10/08/2025
Kate Young
In a recent study, exposure to fine particulate matter (PM2.5) was associated with both more advanced Alzheimer disease neuropathologic change and greater dementia severity, with much of this link mediated...
10/08/2025
Research Summary
Research Summary
09/25/2025
Anthony Calabro, MA
In a phase 3 randomized controlled trial, escitalopram was not associated with significant improvement in agitation symptoms in patients with Alzheimer dementia and was linked to QT interval prolongation,...
09/25/2025
FDA Alert
FDA Alert
09/23/2025
Kate Young
The FDA initiated approval of leucovorin calcium tablets to treat cerebral folate deficiency (CFD) following a systematic analysis demonstrating promise in this patient population.
09/23/2025
Research Summary
Research Summary
09/11/2025
Miranda Manier, BA
A large cohort study explored whether semaglutide and tirzepatide influence risks of dementia, stroke, and survival in adults with diabetes and obesity.
09/11/2025
CONFERENCE COVERAGE
CONFERENCE COVERAGE
08/26/2025
Anthony Calabro, MA
Agitation in frontotemporal lobar degeneration is linked to distinct neuropsychiatric symptom profiles between men and women, with men showing a broader spectrum of associated symptoms, particularly in...
08/26/2025
Conference Coverage
Conference Coverage
08/25/2025
Anthony Calabro, MA
New clinical guidance outlines the use of blood-based biomarker tests for Alzheimer’s diagnosis in patients with cognitive impairment, aiming to support more consistent and evidence-based application in...
08/25/2025
Research Summary
Research Summary
08/05/2025
Anthony Calabro, MA
Results from a phase 2B randomized, double-blind, placebo-controlled trial suggest that semaglutide not only reduces inflammation and adiposity in people with HIV but may also provide a neurocognitive...
08/05/2025
Research Summary
Research Summary
08/01/2025
Miranda Manier, BA
A randomized controlled trial reveals that children with ADHD and ASD have distinct gut microbiota signatures, and that probiotic supplementation alters these profiles, offering promising insights for...
08/01/2025
Research Summary
Research Summary
07/30/2025
Kate Young
A large cohort study of adolescents found that higher restricted normalized isotropic (RNI) values—an MRI-based marker of brain microstructure—were associated with greater weight gain over 2 years,...
07/30/2025