Bacterial Infections

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What's Your Diagnosis?
Discrete keratotic, pustular papulonodular lesions with central necrotic crust in differing stages of healing on the lower extremities.
What's Your Diagnosis?
Can You Diagnose the Lesions on This 21-Year-Old Woman’s Lower Extremities After She Returned from the Philippines?
04/27/2026
Peyton Yee, BS; Olivia Cohen, MD, MSPH; Barrett J. Zlotoff, MD
A 21-year-old previously healthy woman presented to the emergency room with a progressive rash on her right leg and was found to be febrile and hypotensive.
04/27/2026
Photo Quiz
An image of the patient’s right lower extremity wounds at the time of admission.
Photo Quiz
Identification of a Chronic Lower Extremity Wound in a Patient With a Mechanical Valve
04/14/2026
Rachel Blansfield, BS; Nicholas Jennelly, MD; Thomas N. Helm, MD
A 54-year-old woman with a history of mitral valve replacement and warfarin therapy presented to the emergency department with worsening right lower extremity pain.
04/14/2026
What's Your Diagnosis?
Red to violaceous nodules with central ulceration and stasis changes on the right lower leg
What's Your Diagnosis?

Mycobacterium Chelonae Infection Diagnosed by PCR in a Patient with Chronic Leg Nodules
04/11/2026
Elen Deng, BS; Mary Helene; Bansri M. Patel, MD; Jeffrey Miller, MD; Thomas N. Helm, MD
A 68-year-old woman presented to the dermatology clinic with a 3-year history of purpuric nodules on the right lower extremity.
04/11/2026

Interactive Features

Photoclinic Challenge
photoclinic
Photoclinic Challenge
Can You Make a Diagnosis Based on This Image?
03/08/2025
A 13-year-old girl was admitted to our emergency department with a 4-day history of worsening conjunctivitis, stomatitis, and odynophagia, leading to decreased oral intake and dehydration.
03/08/2025
Pop Quiz
Bacteria in a petri dish.
Pop Quiz
Blindness From Bacterium
03/04/2023
About 1.9 million people worldwide are affected by this bacterium, which is the leading cause of blindness from an infectious disease. Do you know which bacterium it is?
03/04/2023
otitis media
Ear exam
otitis media
Pediatric Pearls: Treatment for Recurrent Ear Infections
07/07/2022
A 24-month-old boy presents with his parents to the pediatric clinic with an ear infection for the fourth time in the past year. The parents ask if there are any other treatments that may work better at...
07/07/2022
Treatment
Treatment
Pop Quiz: Total Treatment Duration of Drug-Resistant TB
06/03/2022
The ATS/CDC/ERS/IDSA Clinical Practice Guideline on the Treatment of Drug-Resistant Tuberculosis outlines new recommendations for the intensive and continuation phases of treatment. Do you know the...
06/03/2022
Photo Quiz
2006C360_Lymphangitis
Photo Quiz
A Nonhealing Ulcer With Secondary Enlarging Nodules in a Linear Distribution
05/13/2022
A 19-year-old man on active military duty presented with a nonhealing ulcer on his dorsal right hand accompanied by enlarging nodules in a linear distribution on his right arm and forearm.
05/13/2022

Clinical Insights

Case Report Insights
Matthew Nemoy
Case Report Insights
How to Diagnose and Treat a Rare Disease: A Case of Mycobacterium Tuberculosis
07/05/2025
Matthew Nemoy, DO
In this Consultant Case Report Insights, Matthew Nemoy, DO, discusses his team’s study, “Supraclavicular Lymphadenopathy as the Presenting Feature of Disseminated Mycobacterium Tuberculosis,” including the...
07/05/2025
Case Report Insights
Cooper
Case Report Insights
A Case of Bacteremia and Sepsis in a Pediatric Patient
03/24/2025
Drew Burgess; Felicia Cooper, MD
In this Consultant Case Report Insights, Felicia Cooper, MD, and Drew Burgess speak about their study, "Slide Injury Leading to Bacteremia and Sepsis in a Pediatric Patient.” Dr Cooper and Ms Burgess...
03/24/2025
Video
Gerard Slobogean, MD, MPH
Video
Preoperative Skin Antisepsis With Iodine Povacrylex Produced Fewer SSIs Compared With Chlorhexidine Gluconate Among Those With Closed Fracture
11/01/2024
Gerard Slobogean, MD, MPH
In this video, Gerard Slobogean, MD, MPH, reviews his recent study that compared two well-known preoperative skin antisepsis solutions with alcohol for patients with either closed or open extremity...
11/01/2024
Expert Q&A
jacob
Expert Q&A
Increased Risk of Post-Discharge CVD Events Among Survivors of Sepsis
06/09/2024
In this interview, Jacob C. Jentzer, MD, assistant professor of medicine in the Department of Cardiovascular Medicine at the Mayo Clinic in Rochester, Minnesota discusses the implications of his study and...
06/09/2024
Video
Dana Orange
Video
The Presence of Periodontal Disease in Patients With Rheumatoid Arthritis
12/23/2023
In this video, Dana Orange, MD, MSc, and William H. Robinson, MD, PhD, discuss their study, “Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid...
12/23/2023