On May 1, the FDA approved vepdegestrant (Veppanu), a heterobifunctional protein degrader, for adults with estrogen receptor–positive, human epidermal growth factor receptor 2–negative, ESR1-mutated...
The FDA has approved dextromethorphan-bupropion extended-release tablets for agitation associated with Alzheimer disease dementia, offering clinicians a non-antipsychotic treatment option supported by...
The FDA has approved a supplemental indication for lumateperone to reduce relapse risk in adults with schizophrenia based on phase 3 randomized withdrawal data.
A systematic review and meta-analysis evaluated whether pharmacist-led deprescribing interventions reduce polypharmacy and potentially inappropriate medications among older adults across care settings.
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A stepped-wedge cluster randomized trial evaluated whether pairing electronic decision support with routine medication reviews increases deprescribing of potentially inappropriate medications among older...
New guideline recommendations from the ACC/AHA and 9 partner organizations prioritize earlier treatment, refined atherosclerotic cardiovascular disease risk prediction, and broader use of lipid biomarkers...
In a prospective cohort of children in California who were prenatally exposed to selective serotonin reuptake inhibitors (SSRIs), investigators examined whether additional exposure to SSRIs via breast milk...
In this multicenter, phase 3 randomized-controlled trial, researchers evaluated the efficacy and safety of SHR8028, a water-free cyclosporine solution, 0.1%, compared with vehicle in patients with dry eye...
Researchers conducted a meta-analysis to determine the global prevalence of unprescribed weight-loss product use, such as diet pills, among adolescents.
Patients with melanoma and who are being treated with PD-1 inhibitors have an increased risk of experiencing immune-related neurologic adverse events, compared with patients who are not being treated with...
