Research Summaries

Research Summary
Research Summary
05/11/2026
Ashton L. Stahl
In intermediate-risk pulmonary embolism, catheter-directed fibrinolysis lowered early clinical deterioration vs anticoagulation alone.
05/11/2026
Research Summary
Research Summary
05/11/2026
Anthony Calabro, MA
A population-based study examined the associations between short- and intermediate-term environmental exposures and migraine-related encounters.
05/11/2026
Research Summary
Research Summary
05/11/2026
Ashton L. Stahl
In adults with chronic low back pain managed with long-term opioids, a large, randomized, clinical trial evaluated whether mindfulness-based therapy offers superior outcomes compared with cognitive...
05/11/2026
Research Summary
Research Summary
05/08/2026
Anthony Calabro, MA
A phase 3 randomized trial found that Mim8 prophylaxis significantly reduced bleeding rates compared with on-demand therapy and clotting factor prophylaxis in patients with hemophilia A with or without...
05/08/2026
Research Summary
Research Summary
05/08/2026
Anthony Calabro, MA
An individual participant data meta-analysis clarifies which elements of collaborative care most effectively reduce depressive symptoms in primary care, informing implementation strategies for clinicians...
05/08/2026
Timeline Snapshot
physicians discussing cases
Timeline Snapshot
05/07/2026
April 2026 included several FDA drug and biologic approvals across a range of therapeutic areas. This timeline highlights the key alerts our publication covered throughout the month, giving readers a quick,...
05/07/2026
Research Summary
Research Summary
05/06/2026
Kate Young
A randomized clinical trial in Pakistan evaluated whether structured, measurement-based care could accelerate antidepressant response and remission in adults with major depressive disorder compared with...
05/06/2026
FDA Approval
FDA Approval
05/04/2026
Anthony Calabro, MA
On May 1, the FDA approved vepdegestrant (Veppanu), a heterobifunctional protein degrader, for adults with estrogen receptor–positive, human epidermal growth factor receptor 2–negative, ESR1-mutated...
05/04/2026
Research Summary
Research Summary
05/04/2026
Kate Young
A randomized clinical trial evaluated whether a 6-month habit-focused lifestyle program could improve sustained remission of metabolic syndrome at 24 months compared with standard education and activity...
05/04/2026
Research Summary
Research Summary
05/01/2026
Ashton L. Stahl
A phase 3 trial evaluated weekly marstacimab prophylaxis in adolescents and adults with hemophilia A or B with inhibitors.
05/01/2026