A real-world retrospective study found that adding GLP-1 receptor agonists to hormone therapy may reduce endometrial cancer risk in women with benign uterine or endometrial hyperplasia. This study was...
A retrospective cohort study suggested that colchicine prophylaxis at urate-lowering therapy initiation may lower cardiovascular event risk in patients with gout.
In their phase 3, open-label trial, Brown and colleagues set out to address the need for more effective first-line treatment strategies for fit patients with untreated CLL.
Researchers evaluated the safety and efficacy of dolutegravir plus lamivudine in treatment-naive individuals with HIV without baseline resistance testing.
Neoadjuvant nivolumab plus ipilimumab demonstrated improved event-free survival, higher pathologic complete response rates, and lower toxicity compared with chemotherapy in patients with resectable...
A new randomized trial evaluates the impact of integrating pain education into standard physiotherapy care for chronic low back pain, highlighting potential benefits for pain, disability, and well-being.
...
A decade-long follow-up of a landmark trial examining survival outcomes in patients with advanced melanoma treated with nivolumab plus ipilimumab, nivolumab monotherapy, or ipilimumab monotherapy, provides...
A new analysis of national mortality data highlights increases in alcohol-related deaths in the United States from 1999 to 2020, underscoring the urgency of addressing this growing public health crisis.
...
The study findings potentially challenge the conventional wisdom that the risk of Richter transformation would increase as patients with chronic lymphocytic leukemia live longer with novel treatments. This...