Alzheimer Disease

Disease State Hub

Quizzes

Dementia

Quiz: Future Impact of Alzheimer Disease

01/14/2019

New CDC estimates project that the US Alzheimer disease burden will double by what year?

01/14/2019

3-in-30

Answer Key: The Liver–Brain Connection: Understanding Metabolic Pathways in Alzheimer Disease

12/17/2015

Kate Young

Answer Key: 1. True or false: Impaired hepatic function in conditions such as nonalcoholic fatty liver disease (NAFLD) contributes to cognitive decline primarily through reduced bile acid...

12/17/2015

Pop Quiz

Which Intervention Reduces Verbally Agitated Behaviors in Nursing Home Residents With Alzheimer Disease?

12/11/2015

Anthony Calabro, MA

A cluster randomized controlled trial found that a certain intervention reduced agitation in nursing home residents with Alzheimer disease or related dementia compared with those treated with usual care....

12/11/2015

For more on the etiology of Alzheimer disease content, visit our Clinical Update page

The most common type of dementia, Alzheimer disease is a progressive disease that generally begins with mild memory loss and involves parts of the brain that control thought, memory, and language.

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Brain changes may begin 10+ years before symptoms appear. These changes include buildup of proteins that form amyloid plaques and tau tangles. This causes healthy neurons to stop functioning, lose connections with other neurons, and die.

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occupational therapist, neurologist, geriatrician, psychiatrist, primary care physicians, geropsychologist

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Memory loss that disrupts daily life
Difficulty completing familiar tasks at home, at work, or at leisure
Worsening judgment
Misplacing items & failure to retrace steps
Changes in mood, personality, or behavior

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There is no single test to determine AD, but testing options include: computed tomography scan, magnetic resonance imaging, positron emission tomography scan, cerebrospinal fluid analysis, neurological examination

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Examples of cognitive, functional, and behavioral tests include: Ascertain Dementia 8, Activities Questionnaire, Mini-Cog Mini-Mental State Examination, Montreal Cognitive Assessment, Neuropsychiatric Inventory Questionnaire

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Age
Family history
Genetics
Mild cognitive impairment
Modifiable risk factors, like obesity, high cholesterol, poorly controlled type 2 diabetes

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An estimated 6.7 million Americans aged 65 years or older are living with AD (73% are aged 75 years or older)

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By 2025, the number of people aged 65 or older with AD is projected to reach 7.2 million — a 7% increase from 2023.

May 2026

Current Issue

May 2026

Sources

CDC.gov
2023 Alzheimer's Facts and Figures