HIV Management

Resource Center

Research Summaries

Conference Coverage

Conference Coverage

Long-Acting Cabotegravir PrEP Linked to Higher Coverage, Lower HIV Incidence

02/24/2015

Ashton L. Stahl

At CROI 2026 in Denver, CO, investigators reported real-world data from the OPERA cohort comparing cabotegravir long-acting injections with daily oral pre-exposure prophylaxis (PrEP), highlighting...

02/24/2015

Research Summary

Tenofovir Interruptions Linked to Hepatitis B Reactivation Risk in People with HIV in the United States

02/12/2015

Kate Young

A large US cohort study examined hepatitis B virus (HBV) monitoring practices and the risk of HBV reactivation and hepatitis flares during interruptions of tenofovir-containing antiretroviral therapy among...

02/12/2015

HIV Management Snapshot

Reviewed by Daniel Erias, MD & Jeffrey Kwong, DNP, MPH

For more infectious diseases content, visit the Disease State Hub

HIV is an infection caused by an enveloped retrovirus that weakens the immune system by reducing WBCs' ability to fight infections, bacterial infections, and certain cancers. Left untreated, HIV advances to acquired immunodeficiency syndrome.

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Primary care providers, infectious disease specialists, OB/GYN, pharmacists, dietitians, nutritionists, dentists, emergency, family, and internal medicine specialists.

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Those with HIV may experience flu-like symptoms, including: Fever, sore throat, swollen lymph nodes, rash, muscle aches, night sweats, mouth ulcers, chills, and fatigue. However, some with an acute infection may not experience symptoms.

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Despite high accuracy of diagnostic tests, there are no available options for detection immediately following infection. The type of test determines how quickly HIV is detected. Available tests: antibody, antigen/antibody, nucleic acid.

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75% of infectious disease specialists act as primary care for patients with HIV.

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New HIV Diagnoses By Age, 2020

Age 13-24: 20%
Age 25-34: 37%
Age 35-44: 20%
Age 45-54: 13%
Age 55 & older: 10%

Research Summaries

Research Summary

Research Summary

Monthly Long-Acting Cabotegravir–Rilpivirine Reduces Regimen Failure in US Adults with HIV

03/10/2026

In the phase 3 ACTG A5359 LATITUDE trial, investigators evaluated whether monthly, long-acting injectable cabotegravir plus rilpivirine could reduce regimen failure compared with standard oral...

03/10/2026

Research summary

Research summary

Integrase Inhibitor Regimen Demonstrates Non-Inferiority, Fewer Adverse Events in Advanced HIV Disease

12/15/2025

Anthony Calabro, MA

In a large multicountry trial, researchers evaluated whether an integrase inhibitor–based regimen offers comparable or superior treatment outcomes to a boosted protease inhibitor regimen in adults with...

12/15/2025

Disease State Pillar

Disease State Pillar

HIV Management: A Practical Guide for Primary Care

12/09/2025

Miranda Manier, BA

Start fast, suppress durably, and think beyond the viral load: this primary care–focused guide covers diagnosis, same-day antiretroviral therapy, monitoring, opportunistic infection prevention, vaccines,...

12/09/2025

Conference Coverage

Conference Coverage

Patients with HIV Show Lower In-Hospital Mortality After Device-Related Endocarditis

11/18/2025

Kate Young

A national analysis presented at the 2025 AHA Scientific Sessions found that patients with HIV hospitalized with cardiac implantable electronic device–related infective endocarditis had significantly lower...

11/18/2025

Research Summary

Research Summary

Dermatologic Disease Rates Decline Among People With HIV

11/14/2025

Kate Young

A new longitudinal study published in the Journal of the American Academy of Dermatology evaluated more than a decade of data from adults living with HIV, revealing a steady decline in dermatologic disease...

11/14/2025

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