Dermatologic disorders

HS Linked to Schizophrenia, Bipolar Disorder Risk

Hidradenitis suppurativa (HS) is associated with increased risk of mental health disorders, including schizophrenia and bipolar disorder, according to the results of a recent study.

The researchers conducted a nationwide retrospective study including 4381 patients with HS and 39,554 psoriasis and 43248 melanocytic nevi patients as controls. Incidence of HS was 2.7 per 100,000 person years.

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Overall, at least 1 psychiatric diagnosis was reported in 24.1% of patients with HS, compared with 19.1% of those with psoriasis (odds ratio [OR] 1.34 and 13.5% of those with melanocytic nevi (OR 2.04). Mental health disorders were more common in women with HS than in men.

“The main finding of our study is that HS patients have a higher risk for mental disorders than patients with psoriasis. Additionally, this study reveals that HS is associated with both schizophrenia (OR 1.57; CI 1.24-1.98) and bipolar disorder (OR 1.81; CI 1.47-2.23), findings which to our knowledge have not been reported previously,” the researchers concluded.

—Michael Potts


Huilaja L, Tiri H, Jokelainen J, et al. Patients with hidradenitis suppurativa have a high psychiatric disease burden: A Finnish nationwide registry study [published online July 20, 2017]. J Invest Dermatol. doi: 10.1016/j.jid.2017.06.020.