Diabetes Q&A

HS Patients Have A Significantly Higher Risk of Diabetes

Individuals with hidradenitis suppurativa (HS) have a nearly 3-fold higher risk for diabetes, compared with the general population, according to a recent systematic review and meta-analysis.

Currently, little is known about the association between diabetes and HS.

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Therefore, the researchers evaluated 107,050 patients from 14 studies in their systematic review, and 104,373 patients from 7 studies in their meta-analysis. Data were obtained from PubMed, Embase, Cochrane Library, LILACS, and Scielo databases from 1947 to June 13, 2017. All studies included in the systematic review and meta-analysis had reported the prevalence of diabetes mellitus among patients with HS.

Pooled odds ratios were determined with a random effects model, which was used for data analysis. Funnel plot and the Egger test were used to determine publication bias.

Results of the meta-analysis indicated that the prevalence of diabetes was 10.6% in patients with HS, compared with 3.8% in patients without HS. Those with HS had an approximately 3 times higher risk for diabetes vs the general population.

“Hidradenitis suppurativa is significantly associated with an increased prevalence of diabetes mellitus,” the researchers concluded.

—Christina Vogt


Bui TL, Silva-Hirschberg C, Torres J, Armstrong AW. Hidradenitis suppurativa and diabetes mellitus: A systematic review and meta-analysis [Published online October 19, 2017]. J Am Acad Dermatol.