Hereditary Angioedema

Due to its unspecific symptoms, hereditary angioedema is often misdiagnosed and treated with unnecessary surgical procedures.

HAE is mostly caused by mutations in the C1 esterase inhibitor gene, resulting in excessive bradykinin generation. For this reason, researchers hypothesized that use of RNAi to reduce FXII could help to...

In a recent study, researchers sought to evaluate real-world treatment patterns of HAE-specific medications in the US and to assess their impact on healthcare resource utilization.