Managing IBS by Treating the Global Symptom Profile

In this podcast, Darren Brenner, MD, from Northwestern Medicine, discusses the current management of irritable bowel syndrome (IBS), findings from the RELIEF phase 4 clinical trial of diarrhea-predominant IBS (IBS-D), why targeting underlying pathogenic mechanisms of IBS symptoms is the future of management, and more.

Darren Brenner, MD, is an associate professor of medicine and surgery at Feinberg School of Medicine at Northwestern University in Chicago, Illinois.



Brenner DM, Sayuk GS, Gutman CR, et al. Efficacy and safety of eluxadoline in patients with irritable bowel syndrome with diarrhea who report inadequate symptom control with loperamide: RELIEF phase 4 study. Am J Gastroenterol. 2019;114(9):1502-1511. doi:10.14309/ajg.0000000000000327.