cardiovascular disease

Wilson Tang, MD, on the Gut-Heart Axis

In this podcast, Wilson Tang, MD, discusses his research on the gut-heart axis, the role of the gut-heart axis as a potential new target for atherosclerosis therapies, and potential therapeutic implications.

W.H. Wilson Tang, MD, FACC, is assistant professor in medicine at the Cleveland Clinic Lerner College of Medicine, staff in the Section of Heart Failure & Cardiac Transplant Medicine, assistant program director of the General Clinical Research Center (GCRC) at the Cleveland Clinic in Cleveland, Ohio.

Additional Reading:

  • Tang WHW, Wang Z, Levison BS, et al. Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk. N Engl J Med. 2013;368(17):1575-1584. https://doi.org/10.1056/nejmoa1109400
  • Tang WHW, Bäckhed F, Landmesser U, Hazen SL. Intestinal microbiota in cardiovascular health and disease: JACC State-of-the-Art review. J Am Coll Cardiol. 2019;73(16):2089-2105. https://doi.org/10.1016/j.jacc.2019.03.024
  • Wang Z, Bergeron N, Levison BS, et al. Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women. Eur Heart J. 2019;40(7):583-594. https://doi.org/10.1093/eurheartj/ehy799.
  • Wang Z, Klipfell E, Bennett BJ, et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature. 2011;472(7341):57-63. https://doi.org/10.1038/nature09922

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