Chronic Kidney Disease

Could a Sedentary Lifestyle Increase CKD Risk?

A sedentary lifestyle may increase the risk of developing chronic kidney disease (CKD), according to a new study.

Previous research has linked sedentary behavior to diabetes, obesity, and hypertension, but it is still unclear whether it is an independent risk factor for CKD.

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To further investigate this possible relationship, researchers measured the intensity and duration of physical activity of 5873 individuals using data from the National Health and Nutrition Examination Survey.

Overall, 7.9% of the participants were diagnosed with CKD during the course of the study. The average sedentary duration was 34.0 ± 5.6 min/hr. The researchers found that increase of 80 min/day in sedentary duration was associated with a 20% increase in the likelihood of developing chronic kidney disease, independent of the intensity of physical activity, and the presence of comorbidities.

“Sedentary behavior, which is not mere lack of moderate/vigorous physical activity, is likely an independent risk factor for chronic kidney disease,” researchers concluded.

“It needs to be tested whether sedentary behavior affects the progression of chronic kidney disease, and thereby, increases the risk of end stage renal disease. Hence, interventions targeting sedentary behavior to slow the progression of chronic kidney disease need to be conducted.”

—Michael Potts


Ferranti D, Lyden K, Chen X, et al. Sedentary behavior as a risk factor for CKD. Paper presented at: ASN Kidney Week 2015. November 3-8, 2015. San Diego, CA.