Peer Reviewed

What's Your Diagnosis?

​​​​​​​Breathless After Cardiopulmonary Resuscitation: How Would You Diagnose This Patient’s Respiratory Pattern?

  • Answer: Nonintegrated Chest Wall

    A nonintegrated chest wall, or “flail chest,” is due to trauma when 2 or more contiguous ribs are broken in at least 2 places—a common result of chest compressions during CPR.1 This leads to chest wall destabilization and paradoxical rib cage movement. Not only will negative inspiratory force created by the diaphragm attempt to draw in air, but also the inspiratory effort will draw in the unstable “floating” portion of the chest. This will lead to a decrease in tidal volume, leading to hypoxemia, hypercarbia, and respiratory failure.

    The diagnosis is made by inspection of the rib cage and noting paradoxical movement of the chest wall area inward rather than outward during inspiration. In mechanically ventilated patients or in patients receiving noninvasive ventilation, the diagnosis may not be appreciated.

    Treatment includes pain management and positive-pressure ventilation.1 Surgical treatment options for rib fixation can also be attempted.1,2

    As for the differential diagnosis, this patient does not have a pneumothorax, where one would see expansion of the affected hemithorax and a shift of the trachea to the contralateral side. With COPD exacerbation, a patient would have increased thoracic expansion along with accessory muscle use, decreased air movement, and a prolonged expiratory phase. In cardiac tamponade, one would see jugular venous distention, marked hypotension, and muffled heart sounds (the Beck triad).


    1. Drahos A, Fitzgerald M, Ashley D, Christie DB III. Chest wall stabilization with rib plating after cardiopulmonary resuscitation. J Thorac Dis. 2019;11(suppl 8):S1103-S1105. doi:10.21037/jtd.2018.12.51
    2. Slobogean GP, MacPherson CA, Sun T, Pelletier ME, Hameed SM. Surgical fixation vs nonoperative management of flail chest: a meta-analysis. J Am Coll Surg. 2013;216(2):302-11.e1. doi:10.1016/j.jamcollsurg.2012.10.010