risk management

E-Cigarette Use Increases Risk of Prediabetes

The use of e-cigarettes is associated with a greater risk of prediabetes, according results of a recent study.1

Researchers utilized data from the Behavioral Risk Factor Surveillance System survey conducted from 2016 to 2018. A total of 600,046 individuals who completed the prediabetes and e-cigarette modules were included in this analysis. Of the participants, 28.6% were aged older than 35 years, 50.4% were women, 67.7% were non-Hispanic White, and 12.2% were non-Hispanic Black.

The prevalence of prediabetes was 9.0% among current e-cigarette users, 5.9% among sole e-cigarette users, and 10.2% among dual users (both e-cigarettes and combustible-cigarettes). The odds ratio for prediabetes in the fully adjusted model were 1.22 (95% CI, 1.10--1.37) for current users, 1.12 (95% CI, 1.05--1.19) for former users, 1.54 (95% CI, 1.17--2.04) for sole e-cigarette users, and 1.14 (95% CI, 0.97--1.34) for sole e-cigarette users when compared with those who never use e-cigarettes.

“Our study demonstrated a clear association of prediabetes risk with the use of e-cigarettes,” study author Shyam Biswal, PhD, concluded in a press release.2 “With both e-cigarette use and prevalence of prediabetes dramatically on the rise in the past decade, our discovery that e-cigarettes carry a similar risk to traditional cigarettes with respect to diabetes is important for understanding and treating vulnerable individuals.”


—Leigh Precopio



  1. Zhang Z, Jiao Z, Blaha MJ, et al. The association between e-cigarette use and prediabetes: results from the Behavioral Risk Factor Surveillance System, 2016-2018. Am J Prev Med. Published online March March 2, 2022. doi:10.1016/j.amepre.2019.10.014
  2. Evidence links e-cigarette use with increased odds of prediabetes. News release. Elsevier; March 3, 2022. Accessed March 3, 2022. https://www.elsevier.com/about/press-releases/research-and-journals/evidence-links-ecigarette-use-with-increased-odds-of-prediabetes