Coronary Artery Bypass Grafting May Be a Surgical Option for Patients Aged 80 Years or Older
Coronary artery bypass grafting (CABG) in adults aged 80 years or older may have favorable outcomes and increased long-term survival, despite the high risk of this procedure for this patient population.
While there are currently no clear guidelines when looking at the risks and benefits of CABG for adults aged 80 years or older, the researchers aimed to define the risks while also examining the trends in patients in this age group who had the procedure.
Using data spanning from January 1993 to October 2019, investigators studied 1283 consecutive patients who underwent primary isolated CABG. Kaplan-Meier survival probability, quartile estimates, and logistic regression models were used for data analysis. The researchers noted patient comorbidities, including a history of smoking, diabetes, and hypertension.
The survival rates in patients were 90.2% at 1 year, 57.8% at 5 years, 24.9% at 10 years, and 6.9% at 15 years. The researchers noted the surgical mortality rate was 4% (n = 51) with a median survival time of 7.6 years after surgery.
Overall, the researchers found that—after a 1-year follow-up—the survival rate of people who elected to have CABG was significantly higher than population-based rates (P < .001) and survived longer than expected (median = 1.6 years) compared with the general population.
“Although CABG in octogenarians carries a higher surgical risk, it may be associated with favorable outcomes and increase in long-term survival,” the researchers wrote. “Further studies are warranted to define subgroups benefiting more from surgical revascularization.”
Choi K, Locker C, Fatima B, et al. Coronary artery bypass grafting in octogenarians—risks, outcomes, and trends in 1283 consecutive patients. Mayo Clin Proc. Published online June 20, 2022. doi:10.1016/j.mayocp.2022.03.033