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Colonoscopy revealed diverticulosis in a 47-year-old man who had presented with rectal bleeding. A polypoid lesion was noted in the sigmoid colon (A). The mucosa of this lesion—unlike that of a hyperplastic or adenomatous polyp—appeared normal and was similar to the surrounding mucosa. The thin walls easily dimpled with light pressure from the closed biopsy forceps (B). This finding excludes a true polyp and confirms the diagnosis of an inverted diverticulum. The differential diagnosis includes other submucosal lesions, such as leiomyomas (lipomas), which typically have a yellowish hue.
Recognition is important because biopsy of an inverted diverticulum would result in iatrogenic colonic perforation.
- Yusuf SI, Grant C. Inverted colonic diverticulum: a rare finding in a common condition? Gastrointest Endosc. 2000;52:111-115.